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Chain length effect on the binding of amphiphiles to serum albumin and to POPC bilayers

RMS Cardoso, HAL Filipe, F Gomes…

文献索引:Cardoso; Filipe; Gomes; Moreira; Vaz; Moreno Journal of Physical Chemistry B, 2010 , vol. 114, # 49 p. 16337 - 16346

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被引用次数: 26

摘要

The interaction of small molecules, such as drugs or metabolites, with proteins and biomembranes is of fundamental importance for their bioavailability. The systematic characterization of the binding affinity for structurally related ligands may provide rules that allow its prediction for any other relevant molecule. In this work we have studied a homologous series of fluorescent fatty amines with the fluorescent moiety 7-nitrobenz-2- ...