2-Substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase

TM Williams, TM Ciccarone…

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1345 - 1348

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被引用次数: 71

摘要

... Journal of Medicinal ... Departments of Medicinal Chemistry, Cancer Research, and Safety Assessment, Merck Research Laboratories, West Point, Pennsylvania 19486, and Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania ...