New synthesis of carbazole-1, 4-quinone using a tandem ring-closing metathesis and dehydrogenation reaction under oxygen atmosphere, and its application to the …
The ring-closing metathesis (RCM) reaction by Grubbs's group is a well known reaction for the construction of many functionalized carbocycles and heterocycles. 6 To our knowledge, there are few examples that make use of RCM reactions for the construction of carbazole framework from bisallylindoles. 7 We planned a new total synthesis of murrayaquinone A (1) based on the application of the RCM reaction. In this paper, we describe a new methodology for the ...