Abstract Benzene derivatives bearing at least one bulky alkyl group (i-Pr or t-Bu) were selectively and effectively iodinated using elemental iodine activated by 1-(chloromethyl)-4- fluoro-1, 4-diazoniabicyclo [2.2. 2] octane bis (tetrafluoroborate)(Selectfluor TM, F-TEDA-BF 4). Iodine atoms were progressively introduced at the most electron-rich and sterically less hindered position on the benzene ring. Not more than three iodine atoms could be ...