Synthesis

A convergent method for the synthesis of highly enantiomerically enriched cyclic silanes with silicon-centered chirality

M Oestreich, UK Schmid, G Auer, M Keller

文献索引：Oestreich, Martin; Schmid, Ulrike K.; Auer, Gertrud; Keller, Manfred Synthesis, 2003 , # 17 p. 2725 - 2739

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被引用次数: 12

摘要

Abstract A preparatively straightforward methodology has been developed which allows the assembly of silicon-containing carbocycles as mixtures of diastereomers with silicon as the sole center of stereogenic information. One-step construction of the chiral cyclic silanes is realized by reaction of equimolar amounts of a dibromide and a chirally modified dichlorosilane under Barbier conditions giving access to several monofunctionalized 1- ...