Organic letters

Oxidative rearrangement of cyclic tertiary allylic alcohols with IBX in DMSO

M Shibuya, S Ito, M Takahashi, Y Iwabuchi

文献索引：Shibuya, Masatoshi; Ito, Shinichiro; Takahashi, Michiyasu; Iwabuchi, Yoshiharu Organic Letters, 2004 , vol. 6, # 23 p. 4303 - 4306

全文：HTML全文

被引用次数: 68

摘要

A practical and environmentally friendly method for oxidative rearrangement of five-and six- membered cyclic tertiary allylic alcohols to β-disubstituted α, β-unsaturated ketones by the IBX/DMSO reagent system is described. Several conventional protecting groups (eg, Ac, MOM, and TBDPS) are compatible under the reaction conditions prescribed.