Trifluoromethylation of aryl and heteroaryl halides with fluoroform-derived CuCF3: scope, limitations, and mechanistic features

A Lishchynskyi, MA Novikov, E Martin…

文献索引：Journal of Organic Chemistry, , vol. 78, # 22 p. 11126 - 11146

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被引用次数: 63

摘要

... The Journal of Organic Chemistry. ... J. Org. Chem. ... The traditional strategy to use CHF 3 , a weak acid (pK a = 27 in water),(25) in synthesis is based on deprotonation with strong alkali metal(18-22) or electrogenerated(26) organic bases. ...