N-Substituted-2-chloroacetamides have shown high herbicidal activity. 2 As a continuation of the study of the relationship of structure to phytotoxicity, a large number of unreported chloroacyl amides have been synthesized. The amides of Tables I-IV were prepared by the reaction of equivalent amounts of acid chlorides and amines in the presence of aqueous sodium hydroxide at-10 to Oo, usually in a solvent such as sym-tetrachloroethane or l12- ...
