Antimycobacterial thiobenzanilides

K Waisser, N Houngbedji, M Macháček…

文献索引：Waisser, Karel; Houngbedji, Nestor; Machacek, Milos; Sekera, Miroslav; Urban, Josef; Odlerova, Zelmira Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 1 p. 307 - 316

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被引用次数: 19

摘要

Abstract A group of 30 thiobenzanilides active against Mycobacterium kansasii have been synthesized and their 1 H NMR and UV spectra and RM values (TLC on silica gel impregnated with methylsilicone oil) have been measured. From the correlation between the chemical shifts of the thioamide proton in the 1 H NMR spectra and the Hammett constants it can be concluded that the substituents in both aromatic rings uniformly affect the electron ...