The Journal of Organic Chemistry 2017-05-11

Synthesis of 4-Halo-3(2H)-furanones Using Intramolecular Cyclization of Sulfonium Salts

Sho Inagaki, Maiko Nakazato, Nozomi Fukuda, Satoru Tamura, Tomikazu Kawano

文献索引：10.1021/acs.joc.7b00399

全文：HTML全文

摘要

A simple and efficient synthesis of 4-halo-3(2H)-furanones by halogenative intramolecular cyclization of sulfonium salts is described, which can expedite the production of a variety of 4-bromo- or 4-iodo-3(2H)-furanones, useful synthetic building blocks, in good to high yield under mild conditions.