Synlett

New efficient synthesis of 5-ethoxyoxazoles and oxazolo [3, 2-c] quinazolines via aza-wittig reaction

NY Huang, YB Nie, MW Ding

文献索引：Huang, Nian-Yu; Nie, Yi-Bo; Ding, Ming-Wu Synlett, 2009 , # 4 p. 611 - 614

全文：HTML全文

被引用次数: 15

摘要

Abstract 5-Ethoxyoxazoles or 2-acylamino propanoates were synthesized by aza-Wittig reaction of iminophosphorane with acyl chloride in the presence of triethylamine. Reactions of 5-alkoxyoxazole with triphenyphosphine produced iminophosphoranes. A tandem aza- Wittig reaction of iminophosphorane with isocyanate or carbon disulfide generated oxazolo [3, 2-c] quinazolines in satisfactory yields.