… : 6??Chloro??2, 5??diazatetracyclo [8.5. 0.02, 13.04, 9] pentadeca??4, 6, 8??triene??11??one and 6??chloro??2, 7??diazatetracyclo??[8.5. 0.02, 13.04, 9] pentadeca??4, 6, 8??triene?? …

J Cheng, L Xu, ED Stevens, ML Trudell…

文献索引：Cheng, Jie; Xu, Liang; Stevens, Edwin D.; Trudell, Mark L.; Izenwasser, Sari; Wade, Dean Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 4 p. 569 - 574

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被引用次数: 3

摘要

Abstract Two conformationally constrained tropane derivatives were prepared as rigid nicotinic acetylcholine receptor ligands. A palladium catalyzed intramolecular α-arylation reaction was employed to generate the tricyclic compounds in good yields from N-(bromo- chloropyridylmethyl)-8-azabicyclo [3.2. 1] octan-3-ones.