Hypoglycaemic agents

DF Hayman, V Petrow…

文献索引：Hayman,D.F. et al. Journal of Pharmacy and Pharmacology, 1964 , vol. 16, p. 538 - 548

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被引用次数: 5

摘要

Various 3-substituted derivatives of 1-(p-vinylbenzenesulphonyl) urea, l-[p-(Zchloroethyl) benzenesulphonyl] urea and 1-[p-(2-bromoethyl) benzenesulphonyl] urea are described. Several of the compounds possess noteworthy hypoglycaemic activity on oral administration in rabbits. In contrast, several related 5-substituted derivatives of 2-[p-(2-chloroethyl) benzenesulphonamido]-l, 3, 4-thiadiazo~ es and-1, 3, 4-oxadiazoles were virtually ...