The Journal of organic chemistry

Synthesis of a 1'-aminomethylthymidine and oligodeoxyribonucleotides with 1'-acylamidomethylthymidine residues

P Grünefeld, C Richert

文献索引：Dogan, Zeynep; Paulini, Ralph; Stuetz, Jan A. Rojas; Narayanan, Sukunath; Richert, Clemens Journal of the American Chemical Society, 2004 , vol. 126, # 15 p. 4762 - 4763

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被引用次数: 21

摘要

Reported here is a 10-step synthesis of a phosphoramidite building block of 1'- aminomethylthymidine that starts from 2-deoxyribose. The framework of the branched aminonucleoside was elaborated from a known 1-cyano-1-bromo glycosyl donor, whose ...