Diastereoselective synthesis of cis??3??and 3, 5??alkylpyrrolizidines

…, JP Célérier, GÉR Lhommet

文献索引：Provot, Olivier; Celerier, Jean-Pierre; Lhommet, Gerard Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 2 p. 371 - 376

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被引用次数: 7

摘要

Abstract Cis-3 and 3, 5-substituted pyrrolizidines can be prepared from β-enaminolactones. Substituted pyrrolidinoketones lead to these compounds by an amino reductive annelation with a low diastereomeric excess, but a best access to these azabicycles consists in preparing cis-2, 5-disubstituted pyrrolidines which are then transformed into the expected heterocycles.