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Tetrahedron

Synthesis of 6-aryl-2, 4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions

G Cooke, HA de Cremiers, VM Rotello, B Tarbit…

文献索引:Cooke; Augier de Cremiers; Rotello; Tarbit; Vanderstraeten Tetrahedron, 2001 , vol. 57, # 14 p. 2787 - 2789

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被引用次数: 48

摘要

The use of catalytic cross-coupling methodologies for preparing aryl functionalised heterocycles with pharmaceutical, agrochemical, materials and supramolecular applications is a burgeoning field of study. 1 In particular, the so-called Suzuki reaction, 2 which involves the palladium catalysed cross-coupling of heteroaryl-halides with aryl boronic acids, has received considerable recent attention. We are particularly interested in exploiting the versatility of the Suzuki cross- ...