Agents acting on the central nervous system. 19.(+-)-1-(o-and m-Alkanoylphenoxy)-3-(N4-arylpiperazinyl) propan-2-ols as local anesthetics, hypotensives, and …
SN Rastogi, N Anand, PP Gupta…
文献索引：Rastogi,S.N. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, p. 797 - 804
In a study of the synthesis and pharmacological screening of (+)-1-(alkanoylphenoxy)-3-(d- arylpiper-azinyl) propan-2-ols and some related compounds it has been found that o- alkanoyl compounds possess marked hypotensive and local anesthetic activity, rn-alkanoyl compounds showed tranquillizing activity, while p-alkanoyl compounds' have antidepressant activity; this dissociation in biological action is particularly marked in ...
