Enantioselective preparation of polyfunctional secondary allylic alcohols using functionalized dialkylzincs prepared by a copper (I) catalyzed iodine-zinc exchange …
MJ Rozema, C Eisenberg, H Lütjens, R Ostwald…
文献索引：Rozema, Michael J.; Eisenberg, Christina; Luetjens, Henning; Ostwald, Roswitha; Belyk, Kevin; Knochel, Paul Tetrahedron Letters, 1993 , vol. 34, # 19 p. 3115 - 3118
Abstract Catalytic amounts of Cu (I) salts considerably facilitate the iodine-zinc exchange reaction leading to polyfunctional dialkylzincs. The catalytic asymmetric addition of these zinc reagents to a wide range of α, β-unsaturated aldehydes provides polyfunctional allylic alcohols with a high enantioselectivity.
