A new approach to the synthesis of benzothiazole, benzoxazole, and pyridine nucleosides as potential antitumor agents

AI Khodair, NA Al-Masoudi…

文献索引：Khodair, Ahmed I.; Al-Masoudi, Najim A.; Gesson, Jean-Pierre Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 11 p. 2061 - 2076

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被引用次数: 14

摘要

Abstract A modified nitrogen and sulfur glycosylation reaction involving benzothiazole benzoxazole and pyridine nucleoside bases with furanose and pyranose sugars are described. Conformational analysis has been studied by homo-and heteronuclear two- dimensional NMR methods (2D DFQ-COSY, HMQC and HMBC). The N and S sites of glycosylation were determined from the 1H, 13C heteronuclear multiple-quantum ...