One??pot three??component synthesis of tetrasubstituted N—H pyrroles from secondary propargylic alcohols, 1, 3??dicarbonyl compounds and tert??butyl carbamate

V Cadierno, J Gimeno, N Nebra

文献索引：Cadierno, Victorio; Gimeno, Jose; Nebra, Noel Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 1 p. 233 - 236

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被引用次数: 15

摘要

Pyrroles are one of the most prominent heterocyclic compounds, being present as key structural motifs in several natural products (for reviews, see [1]), conducting organic materials (for reviews, see [2]), and bioactive molecules (for reviews, see [3]). Consequently, a large number of general methods have been developed to construct these five-membered heterocycles, including the well-known Knorr, Paal-Knorr, and Hantzch syntheses, 1, 3- ...