Synthesis and antimicrobial activity of N-alkyl and N-aryl piperazine derivatives

P Chaudhary, R Kumar, AK Verma, D Singh…

文献索引：Chaudhary, Preeti; Kumar, Rupesh; Verma, Akhilesh K.; Singh, Devender; Yadav, Vibha; Chhillar, Anil K.; Sharma; Chandra, Ramesh Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 1819 - 1826

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被引用次数: 117

摘要

A series of substituted piperazine derivatives have been synthesized and tested for antimicrobial activity. The antibacterial activity was tested against Staphylococcus aureus (MTCCB 737), Pseudomonas aeruginosa (MTCCB 741), Streptomyces epidermidis (MTCCB 1824) and Escherichia coli (MTCCB 1652), and antifungal activity against Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger. All synthesized compounds showed ...