Design, synthesis, biological activity, and ADME properties of pyrazolo [3, 4-d] pyrimidines active in hypoxic human leukemia cells: a lead optimization study

M Radi, E Dreassi, C Brullo, E Crespan…

文献索引：Journal of Medicinal Chemistry, , vol. 54, # 8 p. 2610 - 2626

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被引用次数: 44

摘要

... Journal of Medicinal Chemistry. ... Dipartimento Farmaco Chimico Tecnologico, University of Siena,Via Alcide de Gasperi 2, I-53100 Siena, Italy. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple ...