Synthesis of 5-Hydroxymethyl-8-methyl-3-(3-aryl-[1, 2, 4] oxadiazol-5-yl)-2 H-pyrano [2, 3-c] pyridin-2-ones and Their Esters

IO Zhuravel, SM Kovalenko, OV Zaremba…

文献索引：Zhuravel, Irina O.; Kovalenko, Sergiy M.; Zaremba, Oleg V.; Detistov, Oleksandr S.; Kovalenko, Svitlana S.; Chernykh, Valentin P. Synthetic Communications, 2008 , vol. 38, # 21 p. 3778 - 3784

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被引用次数: 9

摘要

Oxadiazoles have been the subject of investigation in a number of different therapeutic areas, usually as an alternative for ester or amide functionalities. [1,2,4]Oxadiazoles have been proposed as muscarinic receptor agonist, [ 2 2. Messer , JWS ; Abuh , YF ; Liu , Y. ; Periyasamy , S. ; Ngur , DO ; Edgar , MAN ; El-Assadi , AA ; Sbeih , S. ; Dunbar , PG ; Roknich , S. ; Rho , T. ; Fang , Z. ; Ojo , B. ; Zhang , H. ; Huzl , JJ ; Nagy , PI Synthesis and biological ...