Chemical Communications

Cu-catalyzed stereoselective conjugate addition of arylboronic acids to alkynoates

Y Yamamoto, N Kirai, Y Harada

文献索引：Yamamoto, Yoshihiko; Kirai, Naohiro; Harada, Yu Chemical Communications, 2008 , # 17 p. 2010 - 2012

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被引用次数: 8

摘要

The conjugate addition of organometallic reagents to alkynoates is one of the most efficient methods to obtain synthetically valuable multiply substituted acrylates. For this purpose, organocopper reagents have been typically used, 1 since the first report of Corey's group 2a and others. 2b,c Organocopper-based methods, however, have several limitations: (a) they usually require stoichiometric amounts of the copper source, (b) the stereochemistry of the resulting ...