Fast reductive amination by transfer hydrogenation “on water”

…, D Talwar, C Wang, D Xue, J Xiao

文献索引：Lei, Qian; Wei, Yawen; Talwar, Dinesh; Wang, Chao; Xue, Dong; Xiao, Jianliang Chemistry - A European Journal, 2013 , vol. 19, # 12 p. 4021 - 4029

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被引用次数: 57

摘要

Abstract Reductive amination of various ketones and aldehydes by transfer hydrogenation under aqueous conditions has been developed, by using cyclometallated iridium complexes as catalysts and formate as hydrogen source. The pH value of the solution is shown to be critical for a high catalytic chemoselectivity and activity, with the best pH value being 4.8. In comparison with that in organic solvents, the reductive amination in an aqueous phase is ...