Synthesis of C-and O-prenylated tetrahydroxystilbenes and O-prenylated cinnamates and their action towards cancer cells
N Koolaji, A Abu-Mellal, VH Tran, RK Duke…
文献索引：Koolaji, Nooshin; Abu-Mellal, Abdallah; Tran, Van H.; Duke, Rujee K.; Duke, Colin C. European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 415 - 422
Synthesis of the naturally occurred C-and O-prenylated tetrahydroxystilbenes and O- prenylated cinnamates was carried out by decarbonylative Heck reaction and selenium dioxide catalysed oxidation, respectively. In the decarbonylative Heck synthetic route, fusion of benzoyl chloride and styrene derivatives was catalysed by an N-heterocyclic carbene system generated in situ by palladium acetate and 1, 3-bis (2, 6-diisopropylphenyl) ...
