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The first syntheses of 3-bromofascaplysin, 10-bromofascaplysin and 3, 10-dibromofascaplysin—marine alkaloids from Fascaplysinopsis reticulata and Didemnum sp. …

…, SN Fedorov, OS Radchenko, SV Dubovitskii

文献索引:Zhidkov, Maxim E.; Baranova, Olga V.; Balaneva, Nadezhda N.; Fedorov, Sergey N.; Radchenko, Oleg S.; Dubovitskii, Sergey V. Tetrahedron Letters, 2007 , vol. 48, # 45 p. 7998 - 8000

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被引用次数: 22

摘要

A simple and practical approach for the synthesis of the marine sponge pigment fascaplysin was used for the total syntheses of its natural derivatives, the marine alkaloids 3- bromofascaplysin, 10-bromofascaplysin, and 3, 10-dibromofascaplysin. The conditions of each step were revised, and as a result these compounds were produced by identical procedures with total yields of 40–43%.