Two intermediates in the synthesis of decahydroisoquinolines with NMDA and AMPA receptor antagonist activity

J Zukerman-Schpector, M Vega, I Caracelli…

文献索引：Zukerman-Schpector; Vega; Caracelli; Dias; Fernandes Acta Crystallographica Section C: Crystal Structure Communications, 2001 , vol. 57, # 9 p. 1089 - 1091

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被引用次数: 2

摘要

In 6-methyl-N-(4-nitrobenzoyl)-5, 6-dihydropyridin-2 (1H)-one, C13H12N2O4,(I), the piperidone ring is in a distorted half-chair conformation. In 8-methoxy-3-methyl-N-(4- nitrobenzoyl)-1, 2, 3, 4, 5, 6, 7, 8-octahydroisoquinoline-1, 6-dione, C18H20N2O6,(II), the heterocyclic ring is in a slightly distorted half-boat conformation, while the other six- membered ring is in a distorted chair conformation. Compound (II) presents a strong ...