Synthetic communications

One-pot synthesis of N-protected β-chiral amino alcohols

C Somlai, A Péter, P Forgó, B Penke

文献索引：Somlai, Csaba; Peter, Antal; Forgo, Peter; Penke, Botond Synthetic Communications, 2003 , vol. 33, # 11 p. 1815 - 1820

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被引用次数: 8

摘要

Abstract N-tert-butyloxycarbonyl-S-benzyl-cysteine, N-fluorenylmethyloxy-carbonyl-alanine-, S-trityl-cysteine-, O-tert-butyl-serine-and O-tert-butyl-tyrosine were converted to the corresponding alcohols via sodium borohydride reduction of their in situ formed methyl esters. Enantiopurity of the products was checked by chiral HPLC method.