Molecules

Clean and efficient synthesis of isoxazole derivatives in aqueous media

G Dou, P Xu, Q Li, Y Xi, Z Huang, D Shi

文献索引：Dou, Guolan; Xu, Pan; Li, Qiang; Xi, Yukun; Huang, Zhibin; Shi, Daqing Molecules, 2013 , vol. 18, # 11 p. 13645 - 13653

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被引用次数: 10

摘要

Abstract: A series of 5-arylisoxazole derivatives were synthesized via the reaction of 3- (dimethyl-amino)-1-arylprop-2-en-1-ones with hydroxylamine hydrochloride in aqueous media without using any catalyst. This method has the advantages of easier work-up, mild reaction conditions, high yields, and an environmentally benign procedure.