Tetrahedron Letters

Convenient preparation of naphthyridines from halopyridines: sequential Heck coupling and cyclization

PW Phuan, MC Kozlowski

文献索引：Phuan, Puay-Wah; Kozlowski, Marisa C Tetrahedron Letters, 2001 , vol. 42, # 24 p. 3963 - 3965

被引用次数: 31

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A simple method for the preparation of 1,7-naphthyridine and 1,6-naphthyridine from the corresponding aminopyridine starting materials is presented. ... The cis-decalin scaffold had been identified as a flexible framework for the construction of a wide variety of interesting chiral ligands ...

105752-11-2

3-氨基-4-碘吡啶

253-69-0

1,7-萘啶

General synthetic method for naphthyridines and their N-oxid...

[Numata, Atsushi; Kondo, Yoshinori; Sakamoto, Takao Synthesis, 1999 , # 2 p. 306 - 311]

Optimization of potency and pharmacokinetic properties of te...

[Horne, Daniel B.; Tamayo, Nuria A.; Bartberger, Michael D.; Bo, Yunxin; Clarine, Jeffrey; Davis, Carl D.; Gore, Vijay K.; Kaller, Matthew R.; Lehto, Sonya G.; Ma, Vu V.; Nishimura, Nobuko; Nguyen, Thomas T.; Tang, Phi; Wang, Weiya; Youngblood, Beth D.; Zhang, Maosheng; Gavva, Narender R.; Monenschein, Holger; Norman, Mark H. Journal of Medicinal Chemistry, 2014 , vol. 57, # 7 p. 2989 - 3004]