Deciphering the mechanistic dichotomy in the cyclization of 1-(2-ethynylphenyl)-3, 3-dialkyltriazenes: competition between pericyclic and pseudocoarctate pathways
DB Kimball, TJR Weakley, R Herges…
文献索引：Kimball, David B.; Weakley, Timothy J. R.; Herges, Rainer; Haley, Michael M. Journal of the American Chemical Society, 2002 , vol. 124, # 45 p. 13463 - 13473
The mechanistic aspects of the cyclization of (2-ethynylphenyl) triazenes under both thermal and copper-mediated conditions are reported. For cyclization to an isoindazole, a carbene mechanistic pathway is proposed. The carbene intermediate can react with oxygen, dimerize to give an alkene, or be trapped either intermolecularly (using 2, 3-dimethyl-2- butene to generate a cyclopropane) or intramolecularly (using a biphenyl moiety at the ...
