Orally active cephalosporins and penicillins

EHW Böhme, RE Bambury, RJ Baumann…

文献索引：Boehme, E. H. W.; Bambury, R. E.; Baumann, R. J.; Erickson, R. C.; Harrison, B. L.; et al. Journal of Medicinal Chemistry, 1980 , vol. 23, # 4 p. 405 - 412

全文：HTML全文

被引用次数: 6

摘要

To obtain the compounds listed in Tables I and 11, the above prepared acids were first coupled to the cephalosporin nucleus. Deprotection then gave the desired structures. One or more of the following methods of Scheme IV were used to prepare molecules 12 through 27. Synthesis of 28 was achieved according to Scheme V.