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Furan ring opening—isocoumarine ring closure: A recyclization reaction of 2??carboxyaryldifurylmethanes

VT Abaev, AS Dmitriev, SA Podelyakin…

文献索引:Abaev, Vladimir T.; Dmitriev, Artem S.; Gutnov, Andrey V.; Podelyakin, Sergey A.; Butin, Alexander V. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 5 p. 1195 - 1204

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被引用次数: 31

摘要

Isocoumarine derivatives are an important class of natural lactones possessing many kinds of biological activity [1]. A whole number of synthetic isocoumarines are of great interest as pharmaceuticals with antifungal [2], antibacterial [2b], anticoagulant activity [3], human leukocyte elastase inhibitors [4]. The highly reactive heterocyclic ring of isocoumarine makes it an attractive synthon for the synthesis of other types of hetero-and carbocyclic ...