Synthesis and microbiological activity of 5-methyl-2-[p-substituted phenyl] benzoxazoles

İ Yalçın, E Şener, T Özden, S Özden, A Akın

文献索引：Yalcin, I.; Sener, E.; Oezden, T.; Oezden, S.; Akin, A. European Journal of Medicinal Chemistry, 1990 , vol. 25, # 8 p. 705 - 708

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被引用次数: 82

摘要

Abstract The synthesis and microbiological activity of a series of 5-methyl-2-(p-substituted phenyl) benzoxazoles 7a–7g are described. The in vitro microbiological activity of these compounds was determined against some Gram-positive and Gram-negative bacteria and C albicans. The observed minimum inhibitory concentration (MIC) values of the derivatives were compared to some other 2, 5-disubstituted benzoxazoles and clinically used drugs. ...