Thiohydantoins are sulfur analogs of hydantoins with one or both carbonyl groups replaced by thiocarbonyl groups [1]. Among the known thiohydantoins, 2-thiohydantoins are most notably known due of their wide applications as hypolipidemic [2], anticarcinogenic [3], antimutagenic [4], antithyroidal [5] antiviral (eg, against herpes simplex virus, HSV) [6], human immunodeficiency virus (HIV) [7] and tuberculosis [8]), antimicrobial (antifungal and antibacterial) [9], ...
