The preparation of an extensive series of 1-alkyl and dialkylaminoalkylaminothiaxanthones was undertaken as part of a study on the chemotherapy of schistosomiasis. The compounds were prepared by condensing a I-chlorothiaxanthone with a substituted alkylenediamine at atmospheric pressure. The reqGrcd 1-chlorothiaxanthones were obtained by (a) condensing a thio-or dithiosalicylic acid with a 1-halo-4-methylbenzene;(b) treating a chlorothiophenol ...