An Efficient, Large-Scale Synthesis of Idoxifene {(E)-1-[4-[2-(N-pyrrolidino) ethoxy] phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene}

R McCague, GA Potter, M Jarman

文献索引：Organic Preparations and Procedures International, , vol. 26, # 3 p. 343 - 346

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被引用次数: 13

摘要

... 0 1994 by Organic Preparations and Procedures Inc. 343 ... An alternative method for preparing large quantities of the starting 2-chloroethoxybenzene 2 was also required. ... as previously described.h However, mono-lithiation of 1 ,4-diiodobenzene to prepare 4-iodophenyllithium ...