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Diuretics. IV. 6-Chloro-3-substituted 7-Sulfamoyl-1, 2, 4-benzothiadiazine 1, 1-Dioxides

CW Whitehead, JJ TRAVERSO…

文献索引:Whitehead,C.W. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 2809 - 2813

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被引用次数: 7

摘要

hexylmethyl). The mixed anhydride of trifluoroacetic acid and cyclopentylacetic acid (V. R= cyclopentylmethyl) was prepared by mixing trifluoroacetic anhydride with cyclopentylacetic acid. The crude mixed anhydride reacted with I11 to yield 4-chloro-6- cyclopentylacetylaminobensene-1, 3-disulfonamide. There was no evidence of the other possible product, 4-chloro-6-trifluoroacetylaminobenzene-1, 3-disulfonamide having been ...