Tetrahedron: Asymmetry

Almond oxynitrilase-catalyzed transformation of aldehydes is strongly influenced by naphthyl and alkoxy substituents

G Roda, S Riva, B Danieli

文献索引：Roda, Gabriella; Riva, Sergio; Danieli, Bruno Tetrahedron Asymmetry, 1999 , vol. 10, # 20 p. 3939 - 3949

被引用次数: 25

摘要

Different α-and β-substituted aldehydes have been submitted to the catalytic action of almond oxynitrilase (PaHNL), in order to explore the influence of a stereocenter already present in the substrate on the selectivity of this enzyme. The results indicate that naphthyl and alkoxy substituents in the α-and also in the β-position to the aldehyde group significantly influence the stereochemical outcome of the PaHNL-catalyzed transformation.