Contribution to investigation of antimicrobial activity of styrylquinolines

…, J Jampilek, M Vejsova, M Wolff, B Machura…

文献索引：Cieslik, Wioleta; Musiol, Robert; Nycz, Jacek E.; Jampilek, Josef; Vejsova, Marcela; Wolff, Mariusz; MacHura, Barbara; Polanski, Jaroslaw Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 24 p. 6960 - 6968

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被引用次数: 23

摘要

Series of new ring-substituted styrylquinolines and two oxorhenium complexes were prepared and characterized. The compounds were analyzed using RP-HPLC to determine lipophilicity. Primary in vitro screening of the synthesized compounds was performed against fungal and bacterial strains. Some compounds were active against bacteria at micromolar level and against fungi at submicromolar level. Compounds 5, 7-dichloro-2-[2-(2- ...