Extremely Fast Gas/Liquid Reactions in Flow Microreactors: Carboxylation of Short??Lived Organolithiums

…, Y Takahashi, J Yoshida

文献索引：Nagaki, Aiichiro; Takahashi, Yusuke; Yoshida, Jun-Ichi Chemistry - A European Journal, 2014 , vol. 20, # 26 p. 7931 - 7934

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被引用次数: 31

摘要

Abstract Carboxylation of short-lived organolithiums bearing electrophilic functional groups such as nitro, cyano, and alkoxycarbonyl groups with CO 2 to give carboxylic acids and active esters was accomplished in a flow microreactor system. The successful reactions indicate that gas/liquid mass transfer and the subsequent chemical reaction with CO 2 are extremely fast.