Chemical and pharmaceutical bulletin

Palladium-catalyzed allylation of acidic and less nucleophilic anilines using allylic alcohols directly

YC Hsu, KH Gan, SC Yang

文献索引：Hsu, Yi-Chun; Gan, Kim-Hong; Yang, Shyh-Chyun Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 10 p. 1266 - 1269

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被引用次数: 22

摘要

The direct activation of C–O bonds in allylic alcohols by palladium complexes has been accelerated by carrying out the reactions in the presence of titanium (IV) isoproxide and 4 Å molecular sieves. The acidic and less nucleophilic anilines such as diphenylamine, phenothiazine, 4-cyanoaniline, and nitroanilines are efficiently allylated under palladium catalysis using allylic alcohols as allylating reagents.