Abstract Three series of novel chiral tetraphenylethenes have been prepared: citronellyl- derived ethers 1a, b, lactate-derived ethers 2d, g, h, i and lactate-derived esters 3a–c, e–h. Helical twisting powers (HTPs) were determined for those derivatives of 1–3, which were sufficiently miscible with the nematic host 5CB 13 or the discotic nematic host hexayne 14. For binary solutions HTP values of 5.7–10.4 µm− 1 for 13/1, 12.8–16.5 µm− 1 for 13/2, 8.0 ...