The Journal of Organic Chemistry

Synthesis of sugars by aldolase-catalyzed condensation reactions

CH Wong, GM Whitesides

文献索引：Wong, Chi-Huey; Whitesides, George M. Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3199 - 3205

全文：HTML全文

被引用次数: 125

摘要

Dihydroxyacetone phosphate was prepared in 200-mmol scale from dihydroxyacetone by two procedures: reaction with phosphorus oxytrichloride and glycerol kinase catalyzed phosphorylation using ATP with in situ regeneration of ATP by phosphoenolpyruvate or acetyl phosphate. Dihydroxyacetone phosphate was converted to fructose 6-phosphate in 80% yield by exposure to a mixture of co-immobilized triosephosphate isomerase and ...