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Protected lactam-bridged dipeptides for use as conformational constraints in peptides

RM Freidinger, DS Perlow…

文献索引:Journal of Organic Chemistry, , vol. 47, # 1 p. 104 - 109

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被引用次数: 240

摘要

... Chem. ... The organic layer was washed further with aqueous citric acid (2 X 100 mL), 1 N NaHC03 (2 X 100 mL), and saturated aqueous NaCl(100 mL). ... when the mixture was allowed to stand: mp 74-76 OC: NMR (CDC1,) 6 1.43 (s,9), 1.2-2.1 (m, 8), 2.07 (s, 3), 2.54 (t, 2, J = 7 Hz ...