Monatshefte für Chemie-Chemical Monthly

Enantioselective synthesis of 3-hydroxytetradecanoic acid and its methyl ester enantiomers as new antioxidants and enzyme inhibitors

HB Kücük, A Yusufoğlu

文献索引：Kuecuek, Hatice Baspinar; Yusufoglu, Ayse Monatshefte fur Chemie, 2013 , vol. 144, # 7 p. 1087 - 1091

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被引用次数: 3

摘要

Abstract Optically pure R and S enantiomers of 3-hydroxytetradecanoic acid and its methyl esters were synthesised by porcine pancreas lipase catalysed hydrolysis of racemic methyl 3-hydroxytetradecanoate in aqueous medium, with the aim of determining their antioxidant, antielastase and antiurease activities. The effects of the weight ratio of substrate/lipase and the reaction time were investigated. Optimum reaction conditions were determined. The ...