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Tetrahedron

Convenient synthesis of 7′ and 6′-bromo-D-tryptophan and their derivatives by enzymatic optical resolution using D-aminoacylase

Y Konda-Yamada, C Okada, K Yoshida, Y Umeda…

文献索引:Konda-Yamada, Yaeko; Okada, Chiharu; Yoshida, Kiminari; Umeda, Yasuyuki; Arima, Shiho; Sato, Noriko; Kai, Toshitsugu; Takayanagi, Hiroaki; Harigaya, Yoshihiro Tetrahedron, 2002 , vol. 58, # 39 p. 7851 - 7861

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被引用次数: 43

摘要

Compounds 7′ and 6′-bromo-d-tryptophan (1 and 2) which are important derivatives for the synthesis of the chloropeptin and kistamycin A, respectively, were conveniently synthesized by optical resolution from N-acetyl-7′ and 6′-bromo-dl-tryptophan ((RS)-5 and (RS)-14) using d-aminoacylase.