Carbohydrate research

Studies on the sialylation of galactoses with different C-5 modified sialyl donors

J Gong, H Liu, JM Nicholls, X Li

文献索引：Gong, Jianzhi; Liu, Han; Li, Xuechen; Nicholls, John M. Carbohydrate Research, 2012 , vol. 361, p. 91 - 99,9

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被引用次数: 6

摘要

Synthetic sialylated glycans provide useful tools to study carbohydrate-mediated biological recognition; however chemical sialylation is the most challenging practice in preparative carbohydrate chemistry, which is often associated with low yields and poor stereoselectivity. Herein, we conducted extensive studies on sialylation with five types of 5-N-modified sialyl donors and four types of galactosyl acceptors. Our studies have shown that a good ...