Tetrahedron letters

Practical synthesis of (R)-γ-amino-β-hydroxybutanoic acid (GABOB) from (R)-epichlorohydrin

S Takano, M Yanase, Y Sekiguchi, K Ogasawara

文献索引：Takano, Seiichi; Yanase, Masashi; Sekiguchi, Yoshinori; Ogasawara, Kunio Tetrahedron Letters, 1987 , vol. 28, # 16 p. 1783 - 1784

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被引用次数: 50

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... (R)-Epichlorohydrin has efficiently been converted to the hypotensive and antiepileptic compound, (R)-γ-amino-β-hydroxybutanoic acid (GABOB), in six steps in 57% overall yield. ... Efficient Conversion of (R)-epichlorohydrin into (R)-GABOB. ... ) was prepared in 73% ...